ROADMAP and ORIENTAL Trials: The Re-emergence of J-Curve Ghost?
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ROADMAP and ORIENTAL Trials: the Re-emergence of J-Curve Ghost?
It still remains unknown whether angiotensin-receptor blockers (ARBs) are cardioprotective in patients with type 2 diabetes. The recent two clinical trials, the ROADMAP and the ORIENT, have suggested that fatal cardiovascular events or cardiovascular deaths were unexpectedly higher in olmesartan group. These results suggest that aggressive blood pressure lowering may cause a higher risk in some...
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ژورنال
عنوان ژورنال: Japanese Clinical Medicine
سال: 2011
ISSN: 1179-6707,1179-6707
DOI: 10.4137/jcm.s7521